CYP46A1 purified MaxPab rabbit polyclonal antibody (D01P)
产品名称： CYP46A1 purified MaxPab rabbit polyclonal antibody (D01P)
英文名称： CYP46A1 purified MaxPab rabbit polyclonal antibody (D01P)
产品编号： H00010858-D01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human CYP46A1 protein.
- Immunogen:
- CYP46A1 (NP_006659.1, 1 a.a. ~ 500 a.a) full-length human protein.
- Sequence:
- MSPGLLLLGSAVLLAFGLCCTFVHRARSRYEHIPGPPRPSFLLGHLPCFWKKDEVGGRVLQDVFLDWAKKYGPVVRVNVFHKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTVFGERLFGQGLVSECNYERWHKQRRVIDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTYTAMDILAKAAFGMETSMLLGAQKPLSQAVKLMLEGITASRNTLAKFLPGKRKQLREVRESIRFLRQVGRDWVQRRREALKRGEEVPADILTQILKAEEGAQDDEGLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLDFEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNPDRFGPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRLVPGQRFGLQEQATLKPLDPVLCTLRPRGWQPAPPPPPC
- Host:
- Rabbit
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of CYP46A1 expression in transfected 293T cell line (H00010858-T02) by CYP46A1 MaxPab polyclonal antibody.
Lane 1: CYP46A1 transfected lysate(56.80 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 10858
- GeneBank Accession#:
- NM_006668
- Protein Accession#:
- NP_006659.1
- Gene Name:
- CYP46A1
- Gene Alias:
- CP46,CYP46
- Gene Description:
- cytochrome P450, family 46, subfamily A, polypeptide 1
- Omim ID:
- 604087
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. [provided by RefSeq
- Other Designations:
- cholesterol 24-hydroxylase,cytochrome P450, family 46,cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase)
- Gene Pathway
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Cardiovascular Diseases
- Cerebral Amyloid Angiopathy
- Cognition Disorders
- Diabetes Complications
- Disease Progression
- Genetic Predisposition to Disease
- Macular Degeneration
- Mental Status Schedule
- Metabolic Syndrome X
- Neoplasms
- Osteoporosis
- Postmortem Changes
- Psychiatric Status Rating Scales