PRKCB monoclonal antibody, clone A10-F
产品名称： PRKCB monoclonal antibody, clone A10-F
英文名称： PRKCB monoclonal antibody, clone A10-F
产品编号： MAB1630
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit monoclonal antibody raised against synthetic peptide of PKC-beta 1.
- Immunogen:
- A synthetic peptide corresponding to human PKC-beta 1.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Isotype:
- IgG
- Storage Buffer:
- In 20 mM Tris-HCl, pH 8.0 (10 mg/mL BSA, 0.05% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (1:5000)
ELISA (1:20000-1:50000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Application Image
- Western Blot
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemistry (Frozen sections)
- Immunofluorescence
- enlarge
- Immunoprecipitation
- ELISA
- Entrez GeneID:
- 5579
- Gene Name:
- PRKCB
- Gene Alias:
- MGC41878,PKC-beta,PKCB,PRKCB1,PRKCB2
- Gene Description:
- protein kinase C, beta
- Omim ID:
- 176970
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
- Other Designations:
- protein kinase C, beta 1 polypeptide
- Gene Pathway
- B cell receptor signaling pathway
- Calcium signaling pathway
- Chemokine signaling pathway
- ErbB signaling pathway
- Fc epsilon RI signaling pathway
- Fc gamma R-mediated phagocytosis
- Focal adhesion
- Gap junction
- Glioma
- GnRH signaling pathway
- Leukocyte transendothelial migration
- Long-term depression
- Long-term potentiation
- MAPK signaling pathway
- Melanogenesis
- Natural killer cell mediated cytotoxicity
- Non-small cell lung cancer
- Pathways in cancer
- Phosphatidylinositol signaling system
- Tight junction
- Vascular smooth muscle contraction
- VEGF signaling pathway
- Vibrio cholerae infection
- Wnt signaling pathway
- Related Disease
- Albuminuria
- Autistic Disorder
- Cardiovascular Diseases
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Diabetic Angiopathies
- Diabetic Nephropathies
- Diabetic Retinopathy
- Disease Progression
- Edema
- Epilepsies, Partial
- Genetic Predisposition to Disease
- Kidney Failure, Chronic
- Liver Cirrhosis
- Proteinuria
- Syndrome
- Tobacco Use Disorder