NEK8 polyclonal antibody
产品名称： NEK8 polyclonal antibody
英文名称： NEK8 polyclonal antibody
产品编号： PAB2619
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of NEK8.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human NEK8.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Nek8 mutation causes overexpression of galectin-1, sorcin, and vimentin and accumulation of the major urinary protein in renal cysts of jck mice.
Valkova N, Yunis R, Mak SK, Kang K, Kultz D.Mol Cell Proteomics. 2005 Jul;4(7):1009-18. Epub 2005 May 4.
- 2.
- Nek8, a NIMA family kinase member, is overexpressed in primary human breast tumors.
Bowers AJ, Boylan JF.Gene. 2004 Mar 17;328:135-42.
- 3.
- Purification, cloning, and characterization of Nek8, a novel NIMA-related kinase, and its candidate substrate Bicd2.
Holland PM, Milne A, Garka K, Johnson RS, Willis C, Sims JE, Rauch CT, Bird TA, Virca GD.J Biol Chem. 2002 May 3;277(18):16229-40. Epub 2002 Feb 25.
- Entrez GeneID:
- 284086
- Protein Accession#:
- NP_835464;Q86SG6
- Gene Name:
- NEK8
- Gene Alias:
- JCK,MGC138445,NEK12A
- Gene Description:
- NIMA (never in mitosis gene a)- related kinase 8
- Omim ID:
- 609799
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the serine/threionine protein kinase family related to NIMA (never in mitosis, gene A) of Aspergillus nidulans. The encoded protein may play a role in cell cycle progression from G2 to M phase. Mutations in the related mouse gene are associated with a disease phenotype that closely parallels the juvenile autosomal recessive form of polycystic kidney disease in humans. [provided by RefSeq
- Other Designations:
- NIMA-family kinase NEK8,NIMA-related kinase 12a,NIMA-related kinase 8,serine/thrionine-protein kinase NEK8