HSD3B7 polyclonal antibody (A01)
产品名称： HSD3B7 polyclonal antibody (A01)
英文名称： HSD3B7 polyclonal antibody (A01)
产品编号： H00080270-A01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a partial recombinant HSD3B7.
- Immunogen:
- HSD3B7 (NP_079469, 101 a.a. ~ 209 a.a) partial recombinant protein with GST tag.
- Sequence:
- IHEVNVQGTRNVIEACVQTGTRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRKVRGGLPLVTCALRPTGIYGEGHQIMRDFYRQG
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- 50 % glycerol
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (38.1 KDa) .
- MSDS:
Download
- Application Image
- Western Blot (Recombinant protein)
- ELISA
- Entrez GeneID:
- 80270
- GeneBank Accession#:
- NM_025193
- Protein Accession#:
- NP_079469
- Gene Name:
- HSD3B7
- Gene Alias:
- PFIC4,SDR11E3
- Gene Description:
- hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- 3 beta-hydroxy-delta 5-C27-steroid oxidoreductase,3 beta-hydroxysteroid dehydrogenase type VII,3-beta-HSD VII,C(27)-3BETA-HSD,short chain dehydrogenase/reductase family 11E, member 3
- Gene Pathway