IL15 (Human) Recombinant Protein (Q01)
产品名称: IL15 (Human) Recombinant Protein (Q01)
英文名称: IL15 (Human) Recombinant Protein (Q01)
产品编号: H00003600-Q01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
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- 所在区域 : 台湾
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- Specification
- Product Description:
- Human IL15 partial ORF ( AAH18149, 30 a.a. - 129 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- GIHVFILGCFSAGLPKTEANWVNVISDLKKIEDLIQSMHIDATLYTESDVHPSCKVTAMKCFLLELQVISLESGDASIHDTVENLIILANNSLSSNGNVT
- Theoretical MW (kDa):
- 36.63
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
- Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 3600
- GeneBank Accession#:
- BC018149
- Protein Accession#:
- AAH18149
- Gene Name:
- IL15
- Gene Alias:
- IL-15,MGC9721
- Gene Description:
- interleukin 15
- Omim ID:
- 600554
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. [provided by RefSeq
- Other Designations:
- OTTHUMP00000164617
- Related Disease
- Adenocarcinoma
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Bronchial Hyperreactivity
- Bronchiolitis, Viral
- Carcinoma, Non-Small-Cell Lung
- Cardiovascular Diseases
- Celiac Disease
- Connective Tissue Diseases
- Coronary Disease
- Diabetes Mellitus
- Diabetes Mellitus, Type 2
- Edema
- Esophageal Neoplasms
- Fetal Diseases
- Fractures, Bone
- Genetic Predisposition to Disease
- Hematologic Diseases