ZEB1 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
ZEB1 抗体

ZEB1 抗体

商家询价

产品名称： ZEB1 抗体

英文名称： ZEB1 Antibody

产品编号： XY21544-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 ZEB1 抗体Applications

Tested Applications: ELISA, WB, IP
Specificity Reaction: Human,Mouse,Rat; Other species are not tested.Please decide the specificity by homology
Positive WB detected in MCF7 cells, HeLa cells, PC-3 cells
Positive IP detected in MCF-7 cells
Recommended dilution WB : 1:500-1:5000
IP : 1:200-1:2000
 ZEB1 抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev1NextView more validation data
  • 21544-1-AP;MCF7 cellMCF7 cells were subjected to SDS PAGE followed by western blot with 21544-1-AP(ZEB1 antibody) at dilution of 1:500
  • 21544-1-AP;MCF-7 cellsIP Result of anti-ZEB1 (IP:21544-1-AP, 4ug; Detection:21544-1-AP 1:500) with MCF-7 cells lysate 4000ug.
Product Information ZEB1 抗体
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information
Immunogen: ZEB1 fusion protein ag16204 Full Name: Zinc finger E-box binding homeobox 1
Caculated Molecular
Weight:		 1125aa,124 kDa Observed Molecular 
Weight:		 190-210kd
GenbankNo BC112392 GeneID: 6935
Symbol ZEB1 Synonyms AREB6, BZP, DELTA EF1, delta EF1,, Negative regulator of IL2, NIL 2 A, NIL 2 A zinc finger protein, NIL 2A, NIL2A, TCF 8, TCF8, Transcription factor 8, ZEB, ZEB1, ZFHEP, ZFHX1A
Background

ZEB1(zinc-finger-enhancer binding protein 1), which is a members of the Zincfinger-Homeobox (ZFH)-family of repressors, acts as a transcriptional repressor that inhibits interleukin-2 (IL-2) gene expression. Depending on the quantity of cDNA and on the cell type, ZEB1 can enhance or repress the promoter activity of the ATP1A1 gene . Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. The calculated molecular weight of ZEB1 is 124 kDa, but the post phosphorylation of protein is about 190-210 kDa. This is a rabbit polyclonal antibody raised against part of the full length of ZEB1 of human. ZEB1 抗体

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